The Down's Syndrome Medical Interest Group
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Medical Library

SLEEP RELATED UPPER AIRWAY OBSTRUCTION (SrUAO). Key Points.

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(based on conference paper by Dr Martin Samuels at RSM conference April 2001)

  • Occurs in up to 60% of those with Down's syndrome
  • Other disorders of breathing also found. 65-80% of children with DS have nocturnal hypoventilation and/or decreased oxygen saturation
  • Most frequent clinical signs - snoring and chest wall recession. May also have abnormal sleep postures and frequent nocturnal arousals.
  • Restless sleep features in many children both with and without Down's syndrome and with and without SrUAO
  • May be adverse effects on daytime functioning, growth and development.
  • Clinic protocols should include specific enquiry re symptoms of SrUAO on an annual basis.
  • Assessment by observation of sleep (eg using video) and sleep studies as in other children/adults.
  • Sleep study facilities/procedures fragmented and variable throughout UK. May need referral to specialist centre
  • May exacerbate pulmonary hypertension in those with congenital heart disease.
  • May lead to life threatening acute obstructive events particularly if given sedation for any reason.
  • Treatment depends on the individual's clinical problem, but Ts and As may often help. Hospital admission recommended because of increased risk of post surgery airway problems
  • Young children may improve with age

Last updated 14.11.01

This page is also available as a PDF.