Keypoints SRUAO. 14.11.01 SLEEP RELATED UPPER AIRWAY OBSTRUCTION (SrUAO) Key Points (based on conference paper by Dr Martin Samuels at RSM conference April 2001) · Occurs in up to 60% of those with Down's syndrome · Other disorders of breathing also found. 65-80% of children with DS have nocturnal hypoventilation and/or decreased oxygen saturation · Most frequent clinical signs ­ snoring and chest wall recession. May also have abnormal sleep postures and frequent nocturnal arousals. · Restless sleep features in many children both with and without Down's syndrome and with and without SrUAO · May be adverse effects on daytime functioning, growth and development. · Clinic protocols should include specific enquiry re symptoms of SrUAO on an annual basis. · Assessment by observation of sleep (eg using video) and sleep studies as in other children/adults. · Sleep study facilities/procedures fragmented and variable throughout UK. May need referral to specialist centre · May exacerbate pulmonary hypertension in those with congenital heart disease. · May lead to life threatening acute obstructive events particularly if given sedation for any reason. · Treatment depends on the individual's clinical problem, but Ts and As may often help. Hospital admission recommended because of increased risk of post surgery airway problems · Young children may improve with age ---------------------------------------------------------------------------------------------------------------------------------------- DSMIG(UK) 2001 www.dsmig.org.uk 16.01.02