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Medical Library

DOWN SYNDROME : IMMUNISATION

Key Points

This page is also available as a PDF.

Note: This advice is based on the current (July 2013) UK immunisation schedule – it will be revised when any changes are introduced.

Give all vaccines that are part of universal UK schedule:

  • DTaP/IPV/Hib (Diphtheria, Tetanus, Acellular Pertussis, Inactivated Polio and Haemophilus influenzae Type b)
  • Men C (Meningococcal C)
  • PCV (Pneumococcal conjugate vaccine)
  • Rota (Rotavirus)
  • MMR (Measles, Mumps, Rubella)
  • Influenza – for all 2 year olds from September 2013 and all children from 2-16 over the next few years

Strong case for following additional vaccines:

  • Influenza from 6 months – especially those with congenital heart disease or chronic lung disease . Given annually
  • Pneumococcal polysaccharide vaccine from aged2 years , particularly in those with cardiac and respiratory problems
  • RSV prophylaxis according to local guidance , but should include all those with aged 12 months or under at the start of the RSV season who are oxygen dependant or have haemodynamically significant congenital heart disease
Possible case for the following:
  • Hepatitis B Need pre and post vaccine determination of immune status as per local schedules. Advice re timing and local schedules available from local paediatrician

Consider pre-care immunisation for adults going into residential care – accelerated course. (1st 3 doses within one month)

BCG - probably no indication unless in high risk group.

There is increased possibility of non-response to immunisation and this should always be borne in mind.

Updated 2013

This page is also available as a PDF.