DOWN'S SYNDROME : IMMUNISATION. Key Points.

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(based on DSMIG clinical awareness note - J Dennis and D Elliman)

Note: This advice is based on the current (September 2006) immunisation schedule - it will be revised if the UK schedule changes

Give all vaccines that are part of universal UK schedule:

• DTP (Diphtheria, Tetanus, Pertussis)
• Polio
• Hib (Haemophilus influenzae Type b)
• Meningococcal C
• Pneumococcal conjugate vaccine (PCV)
• MMR

There is a strong case for the following additional vaccines:

• Influenza for all
• Pneumococcal polysaccharide vaccine for all over two years old and PCV for all those who have not previously received it.
  

There is a possible case for the following:

• Hepatitis B
  • Need pre and post vaccine determination of immune status as per local schedules. Advice re timing and local schedules available from local paediatrician
  • Consider pre-care immunisation for adults and children going into residential care – accelerated course. (1st 3 doses within one month)
• BCG - probably no indication unless high risk group

There is an increased possibility of non-response to immunisation and this should always be borne in mind.

Updated September 2006.

This page is also available as a PDF.

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