Keypoints immunisation.  September 2001


            DOWN'S SYNDROME : IMMUNISATION
                                                                       Key Points
     (based on DSMIG clinical awareness note- J Dennis and D Elliman)


             Give all vaccines that are part of universal UK
             schedule:
             ·  DTP  (Diphtheria, Tetanus, Pertussis)
             ·  Polio
             ·  Hib  (Haemophilus influenzae Type B)
             ·  Meningococcal C
             ·  MMR  (Measles, Mumps, Rubella)
             ·  BCG  (Bacille Calmette-Guerin for tuberculosis).
                        Probably a case to give neonatally rather than at
                        age 12 ­ 14 years.


             Consider following additional vaccines:
             ·  Influenza for all
             ·  Pneumococcal conjugate vaccine below two years
                        old and then plain polysaccharide vaccine when
                        older
             ·  Hepatitis B  (need pre and post vaccine
                        determination of immune status as per local
                        schedules. Advice re timing and local schedules
                        available from local paediatrician)


             There is increased possibility of non-response to
             immunisation and this should always be borne in
             mind.



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DSMIG (UK) 2001   www.dsmig.org.uk                                                                                                                                16.01.02