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The UK (2000) Growth chartsThese are based on data from around 6000 measurements of 1100 healthy children living throughout the UK and Republic of Ireland. Growth can be charted from term to 18 years. Children with significant cardiac disease or other major pathology were excluded from the study population. In addition, data for those born before 37 completed weeks were excluded up to age two. The charts are therefore representative of healthy children with Down's syndrome living in the UK and Republic of Ireland. How were the centiles compiled?The charts were commissioned by the UK Down's Syndrome Medical Interest Group (DSMIG) and the data collected by Dr Mary Styles on DSMIG's behalf. The centiles were compiled under the guidance of Professor Michael Preece with statistical analysis provided by Professor Tim Cole, both of the Institute of Child Health, London. Data were analysed by Cole's LMS method. Dr Styles' data collection was funded by the Child Growth Foundation and remains the copyright of DSMIG. Action guidelines for overweight and underweight childrenAs many older children with Down's syndrome are overweight we have included on the charts standard BMI charts for age 5 - 18 years. Instructions are given as to how these can be used to indicate if there is a serious problem which requires further assessment/guidance. Information is also given about those with failure to thrive. More information about growth monitoring for children with Down's syndrome is included in the Medical Surveillance Guidelines for people with Down's Syndrome produced by the Down's Syndrome Medical Interest Group.
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