- Large population based studies have shown that a wide range of solid tumours occur significantly less frequently in children and adults with Down syndrome when compared with individuals without Down syndrome
- Some solid tumours seem to be more common; these include germ cell (testicular and ovarian tumours) and retinoblastomas
- Treatment options may need to be individualised with regard to co-morbidities and communication difficulties
- prognosis is often as good or better in people with Down Syndrome
- people with Down syndrome may be more susceptible to complications of chemotherapy.
- Cancer prevention strategies including advice on exercise and weight control will be appropriate, and as for the general population.
- Research into the reasons for the protective effect of Down syndrome in some cancers is ongoing
- Haematological malignancies (ALL and AML) are 10-20 times more common in individuals with Down syndrome, but are very rare over the age of 30 – see Blood Disorders topic page
Presentations at DSMIG Meetings
Materials from meetings are available for members only who need to log in to access them. For details on how to become a member click here.